*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XS9065000
CHEMICAL NAME           : Toluene,
                          4-chloro-3,5-dinitro-alpha,alpha,alpha-trifluoro-
CAS REGISTRY NUMBER     : 393-75-9
BEILSTEIN REFERENCE NO. : 1220937
LAST UPDATED            : 199801
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C7-H2-Cl-F3-N2-O4
MOLECULAR WEIGHT        : 270.56
SYNONYMS/TRADE NAMES :
   * Benzene, 2-chloro-1,3-dinitro-5-(trifluoromethyl)-
   * Benzotrifluoride, 4-chloro-3,5-dinitro-
   * 4-Chloro-3,5-dinitrobenzotrifluoride
   * 4-Chloro-3,5-dinitro-alpha,alpha,alpha-trifluorotoluene
   * 3,5-Dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 930 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AISSAW Annali dell'Istituto Superiore di Sanita.  (Istituto Poligrafico e
   Zecca dello Stato, Piazza Verdi, 10 Rome, Italy)  V.1-    1965-
   Volume(issue)/page/year: 19,351,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 161 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0546185
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 450 mg/kg/3D-I
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
   Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   17,21,1989
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2520 mg/kg/21D-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - normocytic anemia
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   12,105,1986

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 0.05 mg/m3;Skin JAN 1993

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***