*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XP2075000
CHEMICAL NAME           : Thymidine, 2',3'-didehydro-3'-deoxy-
CAS REGISTRY NUMBER     : 3056-17-5
BEILSTEIN REFERENCE NO. : 0618327
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-N2-O4
MOLECULAR WEIGHT        : 224.24
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * BMY 27857
   * D 4T
   * 2',3'-Didehydro-3'-deoxythymidine
   * 2',3'-Dideoxy-2',3'-didehydrothymidine
   * Thymine, 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 20 umol/L
REFERENCE :
   MOPMA3 Molecular Pharmacology.  (Williams & Wilkins Co., 428 E. Preston St.,
   Baltimore, MD 21202) V.1-    1965-  Volume(issue)/page/year: 39,625,1991
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 600 mg/kg/3D (Continuous)
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   18,168,1991
 
                            *** END OF RECORD ***