*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XM8302910
CHEMICAL NAME           : 2-Thiophenecarboxamide,
                          3-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)
                          amino)propoxy)-
CAS REGISTRY NUMBER     : 85032-56-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H25-N3-O3-S
MOLECULAR WEIGHT        : 387.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-(3-(1,1-Dimethyl-2-(indol-3-yl)aethylamino)-2-hydroxypropoxy)-thiophen
     -2-carbonsaeureamid
   *   3-(2-Hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-2-th
     iophenecarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 86 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0065295
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 74 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0065295
 
                            *** END OF RECORD ***