*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ9095113
CHEMICAL NAME           : 4H-Thieno(2,3-b)thiopyran-2-sulfonamide,
                          5,6-dihydro-4-amino-6-methyl-, 7,7-dioxide,
                          monohydrochloride, (4S-trans)-
CAS REGISTRY NUMBER     : 164455-27-0
LAST UPDATED            : 199601
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H12-N2-O4-S3.Cl-H
MOLECULAR WEIGHT        : 332.86
SYNONYMS/TRADE NAMES :
   * N-Deethyldorzolamide hydrochloride
   * L 706803
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >800 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 28,1241,1994
 
                            *** END OF RECORD ***