*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ9007800
CHEMICAL NAME           : 4H-Thieno(3,4-b)(1,5)benzodiazepine,
                          4-methyl-10-(4-methyl-1-piperazinyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 74137-79-4
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H20-N4-S.2Cl-H
MOLECULAR WEIGHT        : 385.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Methyl-10-(4-methyl-1-piperazinyl)-4H-thieno(3,4-b)(1,5)benzodiazepine  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,884,1980
 
                            *** END OF RECORD ***