*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ9007420
CHEMICAL NAME           : 10H-Thieno(2,3-b)(1,5)benzodiazepine,
                          7-fluoro-4-(4-methyl-1-piperazinyl)-2-phenyl-,
                          dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 74162-44-0
LAST UPDATED            : 199103
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H21-F-N4-S.2Cl-H.H2-O
MOLECULAR WEIGHT        : 482.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   7-Fluoro-4-(4-methyl-1-piperazinyl)-2-phenyl-10H-thieno(2,3-b)(1,5)benzo
     diazepine 2HCl H2O
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,878,1980
 
                            *** END OF RECORD ***