*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ9005800
CHEMICAL NAME           : 10H-Thieno(2,3-b)(1,5)benzodiazepine,
                          7,8-difluoro-2-ehtyl-4-(4-methyl-1-piperazinyl)-
CAS REGISTRY NUMBER     : 61325-87-9
BEILSTEIN REFERENCE NO. : 1041028
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H20-F2-N4-S
MOLECULAR WEIGHT        : 362.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   7,8-Difluoro-2-ethyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)be
     nzodiazepine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,878,1980
 
                            *** END OF RECORD ***