*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ7050280
CHEMICAL NAME           : Thiazolium,
                          2,2'-(3-(2-(3-heptyl-4-methyl-4-thiazolin-2-ylidene)e
                          thylidene)propenylene )bis( 3-heptyl-4-methyl-,
                          diiodide
CAS REGISTRY NUMBER     : 3571-88-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C38-H61-N3-S3.2I
MOLECULAR WEIGHT        : 910.00
WISWESSER LINE NOTATION : T5NYSJ A7 E1 BU2UY1U1- BT5K CSJ A7 E1&- BT5K CSJ A7
                          E1 &I 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Kankohso 101
   * NK 19
   * Platonin diiodide
   * Platonin iodide
   * Platonin J
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1539 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   KASHAJ Kanko Shikiso.  Photosensitizing Dyes.  (Kanko Shikiso Kenkyukai, c/o
   Kyoto Daigaku Igakubu Byotigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyu-ku,
   Kyoto 606, Japan)  No. 1-    1949-  Volume(issue)/page/year: (85),43,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   KASHAJ Kanko Shikiso.  Photosensitizing Dyes.  (Kanko Shikiso Kenkyukai, c/o
   Kyoto Daigaku Igakubu Byotigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyu-ku,
   Kyoto 606, Japan)  No. 1-    1949-  Volume(issue)/page/year: (85),43,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   KASHAJ Kanko Shikiso.  Photosensitizing Dyes.  (Kanko Shikiso Kenkyukai, c/o
   Kyoto Daigaku Igakubu Byotigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyu-ku,
   Kyoto 606, Japan)  No. 1-    1949-  Volume(issue)/page/year: (85),43,1976
 
                            *** END OF RECORD ***