*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ6000000
CHEMICAL NAME           : 2-Thiazolidinehexanoic acid, 4-oxo-
CAS REGISTRY NUMBER     : 539-35-5
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H15-N-O3-S
MOLECULAR WEIGHT        : 217.31
WISWESSER LINE NOTATION : T5MV DSTJ E5VQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acidomycin
   * Actithiazic acid
   * Cinnamonin
   * Mycobacidin
   * 4-Oxo-2-thiazolidinehexanoic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   TDKNAF Takeda Kenkyusho Nempo.  Annual Report of the Takeda Research
   Laboratories.  (Osaka, Japan) V.1-28, 1936-69.  For publisher information,
   see TAKHAA.  Volume(issue)/page/year: 14,60,1955
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHBUA9 Pharmaceutical Bulletin.  (Tokyo, Japan)  V.1-5, 1953-57.  For
   publisher information, see CPBTAL.  Volume(issue)/page/year: 1,84,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),143,1980
 
                            *** END OF RECORD ***