*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ4020000
CHEMICAL NAME           : Thiazole, 2,4-diamino-5-phenyl-
CAS REGISTRY NUMBER     : 490-55-1
BEILSTEIN REFERENCE NO. : 0157088
REFERENCE               : 4-27-00-05139 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H9-N3-S
MOLECULAR WEIGHT        : 191.27
WISWESSER LINE NOTATION : T5N CSJ BZ DR& EZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Amifenazol
   * Amiphenazol
   * Amiphenazole
   * Daftazol
   * DAPT
   * Daptazile
   * Daptazole
   * DHA-245
   * 2,4-Diamino-5-phenylthiazole
   * Dizol
   * Fenamizol
   * Phenamizol
   * Phenamizole
   * 5-Phenyl-2,4-thiazolediamine
   * 2,4-Thiazolediamine, 5-phenyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1125,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 290 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory obstruction
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,489,1973
 
                            *** END OF RECORD ***