*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ3952000
CHEMICAL NAME           : Thiazole, 5-(3-chloropropyl)-4-methyl-,
                          1,2-ethanedisulfonate
CAS REGISTRY NUMBER     : 13614-24-9
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H10-Cl-N-S.C2-H6-O6-S2
MOLECULAR WEIGHT        : 365.89
WISWESSER LINE NOTATION : T5N CSJ D3G E1 &WSQ2SWQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(3-Chloropropyl)-4-methylthiazole 1,2-ethanedisulfonate
   * Ethanedisulfonate-1,2 de methyl-4 gamma-chloropropyl-5 thiazole
   * 1,2-Ethanedisulfonic acid, compd. with  
   5-(3-chloropropyl)-4-methylthiazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #003815M
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 191 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 23,369,1965
 
                            *** END OF RECORD ***