*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ3553000
CHEMICAL NAME           : 5-Thiazolecarboxamide,
                          N-(1-methyl-2-(1-piperidinyl)ethyl)-2-(methylthio)-4-
                          phenyl-
CAS REGISTRY NUMBER     : 99822-88-5
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H25-N3-O-S2
MOLECULAR WEIGHT        : 375.59
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   N-(1-Methyl-2-(1-piperidinyl)ethyl)-2-(methylthio)-4-phenyl-5-thiazoleca
     rboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 41,633,1984
 
                            *** END OF RECORD ***