*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ2860000
CHEMICAL NAME           : Thiazole, 2-amino-4-(p-nitrophenyl)-
CAS REGISTRY NUMBER     : 2104-09-8
BEILSTEIN REFERENCE NO. : 0200321
REFERENCE               : 4-27-00-04961 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H7-N3-O2-S
MOLECULAR WEIGHT        : 221.25
WISWESSER LINE NOTATION : T5N CSJ BZ ER DNW
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 2-Amino-4-(p-nitrophenyl)thiazole
   * 2-Thiazolamine, 4-(4-nitrophenyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2150 mg/kg/13W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   54,841,1975
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9600 mg/kg/46W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - leukemia
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   33,1593,1973
 
                            *** END OF RECORD ***