*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI3658000
CHEMICAL NAME           : 1,3,4-Thiadiazole,
                          2-(1,1'-biphenyl-2-yl)-5-(4,5-dihydro-1H-imidazol-2-y
                          l)-
CAS REGISTRY NUMBER     : 110718-58-6
BEILSTEIN REFERENCE NO. : 6419656
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H14-N4-S
MOLECULAR WEIGHT        : 306.41
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(1,1'-Biphenyl-2-yl)-5-(4,5-dihydro-1H-imidazol-2-yl)-1,3,4-thiadiazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD30 - Lethal Dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 31,7,1988
 
                            *** END OF RECORD ***