*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI2277591
CHEMICAL NAME           : 1-Thia-4,8-diazaspiro(4.5)decan-3-one,
                          8-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-
                          4-(4-methylphenyl)-, monohydrochloride
CAS REGISTRY NUMBER     : 24854-55-5
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H26-N2-O3-S.Cl-H
MOLECULAR WEIGHT        : 447.03
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   8-(1,4-Benzodioxan-2-ylmethyl)-3-oxo-4-p-tolyl-1-thia-4,8-diazaspiro(4.5
     )decane hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 91,798,1971
 
                            *** END OF RECORD ***