*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI0100000
CHEMICAL NAME           : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
                          3,3-dimethyl-7-oxo-6-(((2-propenylthio)
                          acetyl)amino)-
CAS REGISTRY NUMBER     : 87-09-2
BEILSTEIN REFERENCE NO. : 0044307
REFERENCE               : 4-27-00-05887 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C13-H18-N2-O4-S2
MOLECULAR WEIGHT        : 330.45
WISWESSER LINE NOTATION : T45 ANV ESTJ CMV1S2U1 F1 F1 GVQ
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Allylmercaptomethylpenicillin
   * Allylmercaptomethylpenicillinic acid
   * Allylthiomethylpenicillin
   * Almecillin
   * Cer-O-Cillin
   * Penicillin AT
   * Penicillin O
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Multiple routes
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 35827 ug/kg/6D-I
TOXIC EFFECTS :
   Vascular - structural changes in vessels
REFERENCE :
   JOALAS Journal of Allergy.  (St. Louis, MO)  V.1-47, 1929-71.  For publisher
   information, see JACIBY.  Volume(issue)/page/year: 31,455,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
REFERENCE :
   JLCMAK Journal of Laboratory and Clinical Medicine.  (C.V. Mosby Co., 11830
   Westline Industrial Dr., St. Louis, MO 63141)  V.1-    1915-
   Volume(issue)/page/year: 34,126,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 6490 ug/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
REFERENCE :
   JLCMAK Journal of Laboratory and Clinical Medicine.  (C.V. Mosby Co., 11830
   Westline Industrial Dr., St. Louis, MO 63141)  V.1-    1915-
   Volume(issue)/page/year: 34,126,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
REFERENCE :
   JLCMAK Journal of Laboratory and Clinical Medicine.  (C.V. Mosby Co., 11830
   Westline Industrial Dr., St. Louis, MO 63141)  V.1-    1915-
   Volume(issue)/page/year: 34,126,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5610 ug/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
REFERENCE :
   JLCMAK Journal of Laboratory and Clinical Medicine.  (C.V. Mosby Co., 11830
   Westline Industrial Dr., St. Louis, MO 63141)  V.1-    1915-
   Volume(issue)/page/year: 34,126,1949
 
                            *** END OF RECORD ***