*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH9802000
CHEMICAL NAME           : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
                          3,3-dimethyl-7-oxo-6-((phenylacetyl) amino)-,
                          (2S-(2-alpha,5-alpha,6-beta))-, compd. with
                          2,5-diphenylpiperazine (2:1)
CAS REGISTRY NUMBER     : 7009-88-3
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H18-N2-O4-S.1/2C16-H18-N2
MOLECULAR WEIGHT        : 953.40
SYNONYMS/TRADE NAMES :
   * Alfadryl
   * Penicillinate de 2,5-diphenyl piperazine
   * Penirazine
   * Phenyracillin
   * Phenyracilline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 16,125,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
   Behavioral - aggression
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 16,125,1958
 
                            *** END OF RECORD ***