*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH8320000
CHEMICAL NAME           : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
                          6-((((2-amino-4-(methylamino)-1,4-
                          dioxobutyl)amino)(4-hydrophenyl)acetyl)amino)-3,3-dim
                          ethyl-7-oxo-
CAS REGISTRY NUMBER     : 63329-59-9
LAST UPDATED            : 198103
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H27-N5-O7-S
MOLECULAR WEIGHT        : 493.59
WISWESSER LINE NOTATION : T45 ANV ESTJ CMVYR DQ&MVYZ1VM1 F1 F1 GVQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(N'-Methylasparaginyl)amoxicillin
   * N(sup 4)-Methyl-D-asparaginylamoxicillin
   * TA-058
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   5,151,1980
 
                            *** END OF RECORD ***