*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH6493850
CHEMICAL NAME           : Theophylline, 8-(4-pyridyl)-
CAS REGISTRY NUMBER     : 1088-64-8
LAST UPDATED            : 198212
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H11-N5-O2
MOLECULAR WEIGHT        : 257.28
WISWESSER LINE NOTATION : T56 BM DN FNVNVJ F1 H1 C- DT6NJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-gamma-Piridilteofillina
   * 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-(4-pyridinyl)-
   * 8-gamma-Pyridyltheophylline
   * 8-(4-Pyridyl)theophylline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 790 mg/kg
TOXIC EFFECTS :
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   103,641,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   103,641,1964
 
                            *** END OF RECORD ***