*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH6394000
CHEMICAL NAME           : Theophylline, 7-(2-oxo-4-piperidinobutyl)-6-thio-,
                          hydrochloride
CAS REGISTRY NUMBER     : 97769-20-5
LAST UPDATED            : 198806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H23-N5-O2-S.xCl-H
MOLECULAR WEIGHT        : 604.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * M & B 6496
   * 7-(2-Oxo-4-piperidinobutyl)-6-thiotheophylline hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 472 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 17,196,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 17,196,1961
 
                            *** END OF RECORD ***