*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5907270
CHEMICAL NAME           : Theophylline, 7-(2-hydroxy-3-piperidinopropyl)-
CAS REGISTRY NUMBER     : 7532-45-8
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H25-N5-O3
MOLECULAR WEIGHT        : 323.45
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-(2-Hydroxy-3-piperidinopropyl)theophylline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 17,475,1965
 
                            *** END OF RECORD ***