*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5134700
CHEMICAL NAME           : Theophylline,
                          7-(4-(4-(2,3-dimethylphenyl)-1-piperazinyl)butyl)-,
                          dihydrochloride
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H32-N6-O2.2Cl-H
MOLECULAR WEIGHT        : 497.53
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-(4-(4-(2,3-Dimethylphenyl)-piperazinyl-(1))-n-butyl)-theophyllin  
   dihydrochlorid
   * 7-(4-(4-(2,3-Dimethylphenyl)-1-piperazinyl)butyl)theophylline  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 353 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #3307395
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 408 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #3307395
 
                            *** END OF RECORD ***