*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5107000
CHEMICAL NAME           : Theophylline,
                          7-(2,3-dihydroxypropyl)-8-(2-(3-oxo-2-indolinylene)hy
                          drazino)-
CAS REGISTRY NUMBER     : 102367-55-5
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H19-N7-O5
MOLECULAR WEIGHT        : 413.44
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ B1YQ1Q F1 H1 DMNU- CT56 BMYVJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-(2,3-Dihydroxypropyl)-8-(2-(3-oxo-2-indolinylene)hydrazino)theophylline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 187 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,407,1981
 
                            *** END OF RECORD ***