*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5091000
CHEMICAL NAME           : Theophylline, 8-chloro-7-hydroxymethyl-, nitrate
                          (ester)
CAS REGISTRY NUMBER     : 63906-66-1
LAST UPDATED            : 199009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H8-Cl-N4-O2.N-O3
MOLECULAR WEIGHT        : 289.66
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ B1ONW CG F1 H1 &WNO
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Chloro-7-hydroxycaffeine nitrate
   * Nitric acid, ester with 8-chloro-1,3-dimethyl-7-hydroxymethylxanthine
   * Xanthine, 8-chloro-1,3-dimethyl-7-hydroxymethyl-, nitrate (ester)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 76,126,1942
 
                            *** END OF RECORD ***