*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH4570000
CHEMICAL NAME           : Theophylline, 8-anilino-7-(2,3-dihydroxypropyl)-
CAS REGISTRY NUMBER     : 78960-47-1
BEILSTEIN REFERENCE NO. : 4582805
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H19-N5-O4
MOLECULAR WEIGHT        : 345.40
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ B1YQ1Q CMR& F1 H1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Anilino-7-(2,3-dihydroxypropyl)theophylline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 485 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,407,1981
 
                            *** END OF RECORD ***