*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL1201300
CHEMICAL NAME           : Avermectin A(sub 1a),
                          22,23-dihydro-5-O-demethyl-23-hydroxy-, (13R,23S)-
CAS REGISTRY NUMBER     : 135680-93-2
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C48-H74-O15
MOLECULAR WEIGHT        : 891.22
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 13-epi-Avm B(sub 2)
   * (13R,23S)-22,23-Dihydro-5-O-demethyl-23-hydroxyavermectin A(sub 1a)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 540 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 35,3873,1992
 
                            *** END OF RECORD ***