*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CK0160000
CHEMICAL NAME           : Atropic acid, 4'-chloro-, 3-tropanyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 6746-91-4
LAST UPDATED            : 198909
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H20-Cl-N-O2.Cl-H
MOLECULAR WEIGHT        : 342.29
WISWESSER LINE NOTATION : T56 A ANTJ A1 GOVYU1&R DG &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Atropic acid, p-chloro-, 1-alpha-H,5-alpha-H-tropan-3-alpha-yl ester,  
   hydrochloride
   * 4'-Chloroatropic acid, 3-tropanyl ester, hydrochloride
   * SKF 21000
   * 1-alpha,5-alpha-Tropan-3-ol, p-chloroatropate (ester), hydrochloride
   * 3-Tropanyl 4'-chloroatropate hydrochloride
   * 3-Tropanyl 2-(p-chlorophenyl)acrylate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 17,83,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17950 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - hair
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 17,83,1973
 
                            *** END OF RECORD ***