*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CJ0140000
CHEMICAL NAME           : Aspidospermidine-3-carboxylic acid,
                          6,7-didehydro-3,20-epoxy-2-hydroxy-, methyl ester,
                          (2- beta,3-alpha,5-alpha,12-beta,19-alpha,20S)-
CAS REGISTRY NUMBER     : 11034-66-5
LAST UPDATED            : 198009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H24-N2-O4
MOLECULAR WEIGHT        : 368.47
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 20-Epimelobaline
   * Vincoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   33GVAL "Catharanthus Alkaloids," Taylor, W.I., and N.R. Farnsworth, eds.,
   New York, Marcel Dekker, 1975  Volume(issue)/page/year: -,73,1975
 
                            *** END OF RECORD ***