*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CI9098500
CHEMICAL NAME           : Aspartic acid, L-
CAS REGISTRY NUMBER     : 56-84-8
BEILSTEIN REFERENCE NO. : 1723530
REFERENCE               : 4-04-00-02998 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C4-H7-N-O4
MOLECULAR WEIGHT        : 133.12
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * (S)-Aminobutanedioic acid
   * L-Aminosuccinic acid
   * Asparagic acid
   * L-Asparagic acid
   * Asparaginic acid
   * L-Asparaginic acid
   * Aspartic acid
   * (L)-Aspartic acid
   * L-(+)-Aspartic acid
   * (S)-Aspartic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 25,569,1991
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25079 mg/kg/7D-C
TOXIC EFFECTS :
   Liver - other changes
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,738,1982
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 372,75,1996

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81861
       No. of Facilities: 803 (estimated)
       No. of Industries: 3
       No. of Occupations: 3
       No. of Employees: 5939 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81861
       No. of Facilities: 634 (estimated)
       No. of Industries: 3
       No. of Occupations: 11
       No. of Employees: 9033 (estimated)
       No. of Female Employees: 6545 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Sperm morphology-human
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***