*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CI6476000
CHEMICAL NAME           : Asbestos, actinolite
CAS REGISTRY NUMBER     : 77536-66-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 17
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Actinolite asbestos
   * Asbestos
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   STRHAV Staub-Reinhaltung der Luft.  (VDI-Verlag GmbH, Postfach 1139, D-4000
   Duesseldorf 1, Fed. Rep. Ger.)  V.26-    1966-  Volume(issue)/page/year:
   39,386,1979
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   STRHAV Staub-Reinhaltung der Luft.  (VDI-Verlag GmbH, Postfach 1139, D-4000
   Duesseldorf 1, Fed. Rep. Ger.)  V.26-    1966-  Volume(issue)/page/year:
   39,386,1979

                              *** REVIEWS ***
 
   ACGIH TLV-Confirmed human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 2 fibers/cc
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 14,11,1977

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 2,17,1973

   IARC Cancer Review:Human Sufficient Evidence
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,106,1987

   IARC Cancer Review:Group 1
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,106,1987

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 5 fb/cc (fb > 5 um)
   DTLWS* "Documentation of the Threshold Limit Values for Substances in
   Workroom Air," Supplements. For publisher information, see 85INA8.
   Volume(issue)/page/year: 3,33,1973

   OSHA-cancer hazard
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1001,1987

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-SWITZERLAND:TWA 1 fiber/ml;Carcinogen JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 fiber/ml/4H JAN 1993
   
   OEL-UNITED KINGDOM:TWA 1.5 fiber/ml/10M JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO ASBESTOS-air:100M TWA 0.1 fb/cc in a 400L air sample
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

                          *** STATUS IN U.S. ***
 
   NIOSH Analytical Method, 1994: Asbestos (bulk) by PLM, 9002; by PCM, 7400;
   by TEM, 7402

 
                            *** END OF RECORD ***