*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CF2275000
CHEMICAL NAME           : Argomycin
CAS REGISTRY NUMBER     : 1402-87-5
LAST UPDATED            : 199201
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H43-N-O7
MOLECULAR WEIGHT        : 469.69
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1750 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   53XPA8 "Proceedings of the International Congress of Chemotherapy, 13th,
   Vienna, 1983," Spitzy, K.H., and K. Karrer, eds., 18 vols., Vienna, Austria,
   Verlag H. Egermann, 1983  Volume(issue)/page/year: 16,285/91,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 172 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TDKNAF Takeda Kenkyusho Nempo.  Annual Report of the Takeda Research
   Laboratories.  (Osaka, Japan) V.1-28, 1936-69.  For publisher information,
   see TAKHAA.  Volume(issue)/page/year: 14,60,1955
 
                            *** END OF RECORD ***