*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CC2853000
CHEMICAL NAME           : Antimonate(2-),
                          bis(mu-(2,3-dihydroxybutanedioato(4)-O(sup 1),O(sup
                          2),O(sup 3),O(sup 4))) di-, stereoisomer, dihydrogen,
                          compd. with piperazine (1:1)
CAS REGISTRY NUMBER     : 52195-07-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 30
MOLECULAR FORMULA       : C8-H4-O12-Sb2.C4-H10-N2.2H
MOLECULAR WEIGHT        : 623.80
WISWESSER LINE NOTATION : QVYO&YO&VO 2 &T6M DMTJ &-SB- 2
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Bilharcid
   * Piperazine diantimony tartrate
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 4 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   23,1451,1974
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 4 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   23,1451,1974
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 28 umol/L
REFERENCE :
   JDGRAX Journal of Drug Research.  (National Organization for Drug Research
   and Control, POB 29, Cairo, Egypt)  V.2-    1969-  Volume(issue)/page/year:
   7(3),27,1975
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 4,83,1982

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.5 mg(Sb)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.5 mg(Sb)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,15,1971

   OSHA PEL (Gen Indu):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-AUSTRIA:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-FINLAND:.TWA  (0.5 mg(Sb)/m3) JAN 1993
   
   OEL-FRANCE:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.5 mg(Sb)/m3 (total dust) JAN 1993
   
   OEL-HUNGARY:STEL 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-POLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-RUSSIA:TWA 0.2 mg(Sb)/m3;STEL 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO ANTIMONY-air:10H TWA 0.5 mg(Sb)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

 
                            *** END OF RECORD ***