*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WY2625000
CHEMICAL NAME           : Tellurium
CAS REGISTRY NUMBER     : 13494-80-9
LAST UPDATED            : 199712
DATA ITEMS CITED        : 38
MOLECULAR FORMULA       : Te
MOLECULAR WEIGHT        : 127.60
WISWESSER LINE NOTATION :  TE
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * NCI-C60117
   * Telloy
   * Tellur
   * Tellurium
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TNONF* TNO-report.  (TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ
   Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands) Volume(issue)/page/year:
   TNO-91-063
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2420 mg/m3/4H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TNONF* TNO-report.  (TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ
   Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands) Volume(issue)/page/year:
   TNO-92-008
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   39,100,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TNONF* TNO-report.  (TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ
   Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands) Volume(issue)/page/year:
   TNO-91-O64
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,107,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,107,1982
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3300 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   EXNEAC Experimental Neurology.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year: 31,1,1971
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1693 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   11,691,1988
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6064 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   11,691,1988
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 13 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 28,1444,1972

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.1 mg/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   TOXICOLOGY REVIEW
   FOREAE Food Research.  (Champaign, IL)  V.1-25, 1936-60.  For publisher
   information, see JFDSAZ.  Volume(issue)/page/year: 7,313,1942

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.1 mg/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,245,1971

   OSHA PEL (Gen Indu):8H TWA 0.1 mg(Te)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.1 mg(Te)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.1 mg(Te)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.1 mg(Te)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 0.1 mg/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.1 mg/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.1 mg/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3 JAN 1993
   
   OEL-FRANCE:TWA 0.1 mg/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.1 mg/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.1 mg/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.1 mg/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.1 mg/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.1 mg/m3;STEL 0.5 mg/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.1 mg/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.1 mg/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO TELLURIUM AND COMPOUNDS-air:10H TWA 0.1 mg/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 71197
       No. of Facilities: 192 (estimated)
       No. of Industries: 5
       No. of Occupations: 8
       No. of Employees: 472 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 71197
       No. of Facilities: 422 (estimated)
       No. of Industries: 10
       No. of Occupations: 16
       No. of Employees: 12284 (estimated)
       No. of Female Employees: 3098 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Elements by ICP, 7300

 
                            *** END OF RECORD ***