*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WY2310000
CHEMICAL NAME           : Tellurate(1-),
                          (1,2-ethanediolato(2-)-O,O')trichloro-, ammonium,
                          (SP-5-22)-
CAS REGISTRY NUMBER     : 106566-58-9
LAST UPDATED            : 199707
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C2-H4-Cl3-O2-Te.H4-N
MOLECULAR WEIGHT        : 312.06
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ammonium trichloro(dioxoethylene-O,O')tellurate
   * AS-101 (pharmaceutical)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   NICRDR Natural Immunity and Cell Growth Regulation. (S. Karger Publishers,
   Inc., 79 Fifth Ave., New York, NY 10003 USA)  V.3-    1984-
   Volume(issue)/page/year: 7,163,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   NICRDR Natural Immunity and Cell Growth Regulation. (S. Karger Publishers,
   Inc., 79 Fifth Ave., New York, NY 10003 USA)  V.3-    1984-
   Volume(issue)/page/year: 7,163,1988
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 96 mg/kg/4W-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - retinal changes (pigmentary
   depositions, retinitis, other)
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 17,799,1989
 
                            *** END OF RECORD ***