*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WR5850000
CHEMICAL NAME           : Sulfone, p-chlorophenyl 2,4,5-trichlorophenyl
CAS REGISTRY NUMBER     : 116-29-0
BEILSTEIN REFERENCE NO. : 2292528
REFERENCE               : 4-06-00-01636 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C12-H6-Cl4-O2-S
MOLECULAR WEIGHT        : 356.04
WISWESSER LINE NOTATION : GR BG DG ESWR DG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Akaritox
   * Aredion
   * Benzene, 1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)-
   * p-Chlorophenyl 2,4,5-trichlorophenyl sulfone
   * 4-Chlorophenyl 2,4,5-trichlorophenyl sulfone
   * p-Chlorophenyl 2,4,5-trichlorophenyl sulphone
   * Duphar
   * ENT 23,737
   * FMC 5488
   * Mition
   * NIA 5488
   * Polacaritox
   * Roztozol
   * Sulfone, 2,4,4',5-tetrachlorodiphenyl
   * Tedion
   * Tedion V-18
   * 2,4,4',5-Tetrachloor-difenyl-sulfon
   * 3,4,6,4'-Tetrachlor-diphenylsulfon
   * 2,4,4',5-Tetrachlor-diphenyl-sulfon
   * 2,4,4',5-Tetrachlorodiphenyl sulfone
   * 2,4,5,4'-Tetrachlorodiphenyl sulfone
   * 2,4,5,4'-Tetrachlorodiphenylsulphone
   * 2,4,4',5-Tetracloro-difenil-solfone
   * Tetradichlone
   * Tetradifon
   * Tetradiphon
   * Tetrafidon
   * V-18
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 566 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 9,119,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RREVAH Residue Reviews.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1962-  Volume(issue)/page/year:
   36,240,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SPEADM Special Publication of the Entomological Society of America.  (4603
   Calvert Rd., College Park, MD 20740)  Volume(issue)/page/year: 78-1,55,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 5,220,1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5040 mg/kg/12W-C
TOXIC EFFECTS :
   Liver - other changes
   Liver - changes in liver weight
   Endocrine - changes in thyroid weight
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 1,113,1973
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1953 mg/kg
SEX/DURATION            : female 6-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-160
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   52,221,1983

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

 
                            *** END OF RECORD ***