*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WN0525000
CHEMICAL NAME : Succinic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester,
sodium salt
CAS REGISTRY NUMBER : 577-11-7
OTHER CAS REGISTRY NOS. : 53023-94-2
LAST UPDATED : 199710
DATA ITEMS CITED : 17
MOLECULAR FORMULA : C20-H38-O7-S.Na
MOLECULAR WEIGHT : 445.63
WISWESSER LINE NOTATION : 2Y2&3OVYSWQ1VO3Y2&2 &-NA-
COMPOUND DESCRIPTOR : Reproductive Effector
Primary Irritant
SYNONYMS/TRADE NAMES :
* Aerosol GPG
* Aerosol OT
* Aerosol OT 75
* Aerosol OT-B
* Alcopol O
* Alphasol OT
* Berol 478
* Bis(ethylhexyl) ester of sodium sulfosuccinic acid
* Bis-2-ethylhexylester sulfojantaranu sodneho
* Bis(2-ethylhexyl)sodium sulfosuccinate
* Bis(2-ethylhexyl) S-sodium sulfosuccinate
* 1,4-Bis(2-ethylhexyl) sodium sulfosuccinate
* Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt
* Celanol DOS 75
* Clestol
* Colace
* Complemix
* Constonate
* Coprol
* Defilin
* Di-(2-ethylhexyl) sodium sulfosuccinate
* Dioctlyn
* Dioctylal
* Dioctyl ester of sodium sulfosuccinate
* Dioctyl ester of sodium sulfosuccinic acid
* Dioctyl-medo forte
* Dioctyl sodium sulfosuccinate
* Dioctyl sulfosuccinate sodium
* Dioctyl sulfosuccinate sodium salt
* Diomedicone
* Diosuccin
* Diotilan
* Diovac
* Docusate sodium
* Doxinate
* Doxol
* D-S-S
* Dulsivac
* Duosol
* 2-Ethylhexyl sulfosuccinate sodium
* Humifen WT 27G
* Konlax
* Kosate
* Laxinate
* Laxinate 100
* Manoxal OT
* Manoxol OT
* Mervamine
* Modane soft
* Molatoc
* Molcer
* Molofac
* Monawet MD 70E
* Monawet MO-70
* Monawet MO-70 RP
* Monawet MO-84 R2W
* Monoxol OT
* Nekal WT-27
* Nevax
* Nikkol OTP 70
* Norval
* Obston
* Rapisol
* Regutol
* Requtol
* Revac
* Sanmorin OT 70
* SBO
* Sobital
* Sodium bis(2-ethylhexyl) sulfosuccinate
* Sodium di-(2-ethylhexyl) sulfosuccinate
* Sodium dioctyl sulfosuccinate
* Sodium dioctyl sulphosuccinate
* Sodium 2-ethylhexylsulfosuccinate
* Sodium sulfodi-(2-ethylhexyl)-sulfosuccinate
* Softil
* Sol sodowej sulfobursztynianu dwu-2-etyloheksylowego
* Soliwax
* Solusol-75%
* Solusol-100%
* Sulfimel DOS
* Sulfosuccinic acid, bis(2-ethylhexyl)ester sodium salt
* SV 102
* Tex-Wet 1001
* Triton GR-5
* Triton GR 7
* Vatsol OT
* Velmol
* Waxsol
* Wetaid SR
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 10 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 82,377,1944
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 250 ug
REACTION SEVERITY : Mild
REFERENCE :
AROPAW Archives of Ophthalmology (Chicago). (AMA, 535 N. Dearborn St.,
Chicago, IL 60610) New series: V.1-44(3), 1929-50; V.64- 1960-
Volume(issue)/page/year: 34,99,1945
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1%
REACTION SEVERITY : Severe
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic
Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947-
Volume(issue)/page/year: 13,469,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 590 mg/kg
TOXIC EFFECTS :
Vascular - structural changes in vessels
REFERENCE :
BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 7,161,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2643 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New
York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 1,89,1977/1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 42 gm/kg/12W-C
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 9,159,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12 gm/kg/30D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 84 mg/kg/24W-I
TOXIC EFFECTS :
Behavioral - food intake (animal)
Gastrointestinal - hypermotility, diarrhea
Related to Chronic Data - death
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 25,175,1943
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 8820 mg/kg
SEX/DURATION : multigeneration
TOXIC EFFECTS :
Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
15,53,1990
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 83280
No. of Facilities: 3817 (estimated)
No. of Industries: 53
No. of Occupations: 74
No. of Employees: 45527 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 83280
No. of Facilities: 11668 (estimated)
No. of Industries: 95
No. of Occupations: 100
No. of Employees: 180694 (estimated)
No. of Female Employees: 49329 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***