*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK2133000
CHEMICAL NAME           : D-Streptamine,
                          O-6-amino-6,7-dideoxy-D-glycero-alpha-D-gluco-heptopy
                          ranosyl-(1-4)-O-
                          (3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyr
                          anosyl-(1-6))-2-deoxy-
CAS REGISTRY NUMBER     : 36889-16-4
BEILSTEIN REFERENCE NO. : 1669189
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H40-N4-O10
MOLECULAR WEIGHT        : 496.64
WISWESSER LINE NOTATION : T6OTJ BYZ1 CQ DQ EQ FO- BL6TJ AZ CQ EZ DO- BT6OTJ CQ
                          DM1 EQ E1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Gentamicin B1
   * Gentamycin B1
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,175,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38KLAC "Structure-Activity Relationship among the Semisynthetic
   Antibiotics,"  Perlman, D., ed., New York, Academic Press, 1977
   Volume(issue)/page/year: -,239,1977
 
                            *** END OF RECORD ***