*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK2120000
CHEMICAL NAME           : D-Streptamine,
                          O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-a
                          lpha-D-mannopyranosyl-
                          (1-4)-O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(
                          1-3)-beta-D-ribofuran osyl-(1-5))- 2-deoxy-
CAS REGISTRY NUMBER     : 36019-37-1
LAST UPDATED            : 198806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C29-H55-N5-O19
MOLECULAR WEIGHT        : 777.89
WISWESSER LINE NOTATION : T6OTJ B1Q CQ DQ EZ FO- BL6TJ AZ DQ EZ CO- BT5OTJ CQ
                          E1Q DO- BT6OTJ CZ DQ F1Z EO- BT6OTJ CQ DQ
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic 503-1
   * Antibiotic 2230C
   * 2230C
   * Mannosylparomomycin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 357 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,135,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1878 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,782,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 357 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,682,1978
 
                            *** END OF RECORD ***