*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WJ5690000
CHEMICAL NAME           : 4,4'-Stilbenediol, alpha,alpha'-diethyl-,
                          bis(dihydrogen phosphate), tetrasodium salt, (E)-
CAS REGISTRY NUMBER     : 4719-75-9
OTHER CAS REGISTRY NOS. : 22032-58-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C18-H18-O8-P2.4Na
MOLECULAR WEIGHT        : 516.26
WISWESSER LINE NOTATION : WPO&OR DY2&UY2&R DOPWO &-NA- 4
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Diethylstilbestrol diphosphate tetrasodium
   * Diethylstilbestrol phosphate tetrasodium
   * 4,4'-Dihydroxy-alpha,alpha'-diethyl-stilben-diphosphate tetrasodium
   * Fosfestrol tetrasodium
   * Honvan tetrasodium
   * Tetrasodium diethylstilbestrol phosphate
   * Tetrasodium fosfestrol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 150 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   42,171,1979
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   42,171,1979
 
TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   42,171,1979

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Rodent dominant lethal

 
                            *** END OF RECORD ***