*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WI2800000
CHEMICAL NAME : Stearic acid
CAS REGISTRY NUMBER : 57-11-4
BEILSTEIN REFERENCE NO. : 0608585
REFERENCE : 4-02-00-01206 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C18-H36-O2
MOLECULAR WEIGHT : 284.54
WISWESSER LINE NOTATION : QV17
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Century 1240
* Cetylacetic acid
* Dar-chem 14
* Emersol 120
* Emersol 132
* Emersol 150
* Formula 300
* Glycon DP
* Glycon S-70
* Glycon S-80
* Glycon S-90
* Glycon TP
* Groco 54
* Groco 55
* Groco 55L
* Groco 58
* Groco 59
* Hydrofol acid 1655
* Hydrofol acid 1855
* Hydrofol 1895
* 1-Heptadecanecarboxylic acid
* HY-Phi 1199
* HY-Phi 1205
* HY-Phi 1303
* HY-Phi 1401
* Hystrene 80
* Hystrene 4516
* Hystrene 5016
* Hystrene 7018
* Hystrene 9718
* Industrene 5016
* Industrene 8718
* Industrene 9018
* KAM 1000
* KAM 2000
* KAM 3000
* Neo-fat 18
* Neo-fat 18-S
* Neo-fat 18-53
* Neo-fat 18-54
* Neo-fat 18-55
* Neo-fat 18-59
* Neo-fat 18-61
* Octadecanoic acid
* n-Octadecanoic acid
* Pearl stearic
* Stearex beads
* Stearic acid
* Stearophanic acid
* Tegostearic 254
* Tegostearic 255
* Tegostearic 272
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 75 mg/3D (Intermittent)
REACTION SEVERITY : Mild
REFERENCE :
85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill,
V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
Volume(issue)/page/year: -,127,1977
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 17,383,1979
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 6(3),321,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 21500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
18,141,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 23 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
18,141,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 17,383,1979
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 313 gm/kg/30W-C
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 14,196,1995
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year:
17,127,1963
*** REVIEWS ***
TOXICOLOGY REVIEW
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60.
For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 69740
No. of Facilities: 31794 (estimated)
No. of Industries: 220
No. of Occupations: 159
No. of Employees: 541742 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7032
No. of Facilities: 136 (estimated)
No. of Industries: 3
No. of Occupations: 11
No. of Employees: 9034 (estimated)
No. of Female Employees: 7670 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 69740
No. of Facilities: 34970 (estimated)
No. of Industries: 239
No. of Occupations: 165
No. of Employees: 1123118 (estimated)
No. of Female Employees: 568888 (estimated)
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Negative: E coli polA without S9
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***