*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WH1433000
CHEMICAL NAME           : Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimid
                          in)-3'-ol, 2',3'-dihydro-1-butyl-
                          3'-(2,5-dimethoxyphenyl)-, dihydrobromide
CAS REGISTRY NUMBER     : 52419-67-7
LAST UPDATED            : 198511
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H33-N3-O3-S.2Br-H
MOLECULAR WEIGHT        : 581.48
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1440 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 11,115,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 11,115,1976
 
                            *** END OF RECORD ***