*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VU2340000
CHEMICAL NAME           : Serpentine (alkaloid), hydroxide, inner salt
CAS REGISTRY NUMBER     : 131-07-7
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H20-N2-O3
MOLECULAR WEIGHT        : 348.43
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Methyl ester of serpentinic acid
   * Serpentine hydroxide, inner salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
   Behavioral - aggression
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 123,168,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 144 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
   Behavioral - aggression
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 123,168,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 166 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
   Behavioral - aggression
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 123,168,1959
 
                            *** END OF RECORD ***