*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WH0194530
CHEMICAL NAME           : Spiro(cyclohexane-1,4'(3'H)pyrimidine)-2'(1'H)-thione
                          , 6'-methyl-
LAST UPDATED            : 198408
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H16-N2-S
MOLECULAR WEIGHT        : 196.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6'-Methylspiro(cyclohexane-1,4'(3'H)pyrimidine)-2'(1'H)-thione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 480 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   24,572,1969
 
                            *** END OF RECORD ***