*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WH0140000
CHEMICAL NAME           : Spirobolus bungii brandt, extract
SUBSTANCE DEFINITION :
   The insect belonging to the family Spiroboludae
REFERENCE :
   JTCMEC Journal of Traditional Chinese Medicine (English Edition). (All-China
   Assoc. of Traditional Chinese Medicine, Academy of Traditional Chinese
   Medicine)  V.1-    1981-
LAST UPDATED            : 199606
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Shanqiong
   * Yanshanqiong
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2733 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JTCMEC Journal of Traditional Chinese Medicine (English Edition). (All-China
   Assoc. of Traditional Chinese Medicine, Academy of Traditional Chinese
   Medicine)  V.1-    1981-  Volume(issue)/page/year: 1,27,1981
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2600 mg/kg/26D-I
TOXIC EFFECTS :
   Liver - other changes
   Liver - changes in liver weight
REFERENCE :
   JTCMEC Journal of Traditional Chinese Medicine (English Edition). (All-China
   Assoc. of Traditional Chinese Medicine, Academy of Traditional Chinese
   Medicine)  V.1-    1981-  Volume(issue)/page/year: 1,27,1981
 
                            *** END OF RECORD ***