*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WG9910500
CHEMICAL NAME           : Spiro(benzo(b)thiophene-2(3H),4'-piperidine),
                          1'-methyl-3-(2-methylphenyl)-, hydrochloride, (+-)-
CAS REGISTRY NUMBER     : 122942-79-4
LAST UPDATED            : 199103
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H23-N-S.Cl-H
MOLECULAR WEIGHT        : 345.96
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (+-)-1'-Methyl-3-(2-methylphenyl)-spiro(benzo(b)thiophene-2(3H),4'-piper
     idine) hydrochloride
   * 1'-Methyl-3-(o-tolyl)-spiro(benzo(b)thiophene-2(3H)-4'-piperidine)  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 226 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 54,235,1989
 
                            *** END OF RECORD ***