*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WG9900000
CHEMICAL NAME           : Spiro(4H-3,1-benzothiazine-4,1'-cyclohexane),
                          5,6,7,8-tetrahydro-2-amino-, mono(o-chlorobenzoate)
CAS REGISTRY NUMBER     : 28358-21-6
LAST UPDATED            : 198406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H20-N2-S.C7-H5-Cl-O2
MOLECULAR WEIGHT        : 392.98
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   24,572,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 522 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   24,572,1969
 
                            *** END OF RECORD ***