*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WG9862000
CHEMICAL NAME           : Spiro(benzofuran-3(2H),4'-piperidine)-2-one,
                          7-hydroxy-1'-methyl-, hydrochloride
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H15-N-O3.Cl-H
MOLECULAR WEIGHT        : 269.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Hydroxy-1'-methylspiro(benzofuran-3(2H),4'-piperidine)-2-one  
   hydrochloride
   * 1-Methyl-4-(2',3'-dihydroxyphenyl)-4-carboxypiperidine-gamma-lactone  
   hydrochloride
   * NU-541
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 289 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,195,1947
 
                            *** END OF RECORD ***