*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VV1302500
CHEMICAL NAME           : Silanamine, N,N'-methane tetraylbis(1,1,1-trimethyl-
CAS REGISTRY NUMBER     : 1000-70-0
BEILSTEIN REFERENCE NO. : 2042082
LAST UPDATED            : 199704
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C7-H18-N2-Si2
MOLECULAR WEIGHT        : 186.45
SYNONYMS/TRADE NAMES :
   * Bis(trimethylsilyl)carbodiimide
   * Carbodiimide, bis(trimethylsilyl)-
   * N,N'-Methane tetraylbis(1,1,1-trimethylsilanamine)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1728 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - ataxia
   Blood - hemorrhage
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 55(6),86,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1728 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - ataxia
   Blood - hemorrhage
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 55(6),86,1990
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 5190 mg/kg/30D-I
TOXIC EFFECTS :
   Cardiac - other changes
   Liver - liver function tests impaired
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 55(6),86,1990

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***