*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WG9635000
CHEMICAL NAME           : Spiro(8-azoniabicyclo(3.2.1)octane-8,1'-morpholinium)
                          , 3-hydroxy-, chloride, benzilate
CAS REGISTRY NUMBER     : 74033-45-7
LAST UPDATED            : 198812
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H30-N-O4.Cl
MOLECULAR WEIGHT        : 444.01
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-Hydroxyspiro(8-azoniabicyclo(3.2.1)octane-8,1'-morpholinium) chloride  
   benzilate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - ganglion blocker
   Autonomic Nervous System - parasympatholytic
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 16,1581,1966
 
                            *** END OF RECORD ***