*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VW6200000
CHEMICAL NAME           : Simethicone
CAS REGISTRY NUMBER     : 8050-81-5
LAST UPDATED            : 199504
DATA ITEMS CITED        : 3
SYNONYMS/TRADE NAMES :
   * Antifoam A
   * DC antifoam A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   AMSGAO AMA Archives of Surgery.  (Chicago, IL)  V.61-80, 1950-60.  For
   publisher information, see ARSUAX.  Volume(issue)/page/year: 78,220,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
REFERENCE :
   AMSGAO AMA Archives of Surgery.  (Chicago, IL)  V.61-80, 1950-60.  For
   publisher information, see ARSUAX.  Volume(issue)/page/year: 78,220,1959

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4515
       No. of Facilities: 1163 (estimated)
       No. of Industries: 6
       No. of Occupations: 20
       No. of Employees: 90654 (estimated)
       No. of Female Employees: 75193 (estimated)

 
                            *** END OF RECORD ***